FAM5C Contributes to Aggressive Periodontitis

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FAM5C Contributes to Aggressive Periodontitis

Aggressive periodontitis is characterized by a rapid and severe periodontal destruction in young systemically healthy subjects. A greater prevalence is reported in Africans and African descendent groups than in Caucasians and Hispanics. We first fine mapped the interval 1q24.2 to 1q31.3 suggested as containing an aggressive periodontitis locus. Three hundred and eighty-nine subjects from 55 ped...

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Aggressive periodontitis

At the "International Workshop for a Classification of Periodontal Diseases and Conditions" in 1999, the classification of periodontal diseases was revised (Armitage 1999). The various types of periodontitis were divided into three main categories (chronic, aggressive, and necrotizing periodontitis) as well as into a periodontal a manifestation of systemic diseases. This article provides a syno...

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Myeloperoxidase (MPO) is a lysosomal enzyme found in the azurophilic granules of polymorphonuclear leukocytes. It is involved in the defense against periodontal bacteria, and is also able to mediate inflammatory tissue destruction in aggressive and chronic periodontitis. The aim of this study was to explore the association between MPO-463G/A gene polymorphism and aggressive periodontitis (AgP) ...

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Treatment of aggressive periodontitis.

Despite etiological differences between aggressive and chronic periodontitis, the treatment concept for aggressive periodontitis is largely similar to that for chronic periodontitis. The goal of treatment is to create a clinical condition that is conducive to retaining as many teeth as possible for as long as possible. When a diagnosis has been made and risk factors have been identified, active...

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Aggressive periodontitis, which encompasses a number of clinical entities, probably results from the mobilization of tissue‟s destructive mechanisms which are common to most forms of periodontal diseases. The unique attributes of the disease process are due to the virulence of the pathogens and the host susceptibility may be due to the heritable or acquired susceptibility factors, which permit ...

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ژورنال

عنوان ژورنال: PLoS ONE

سال: 2010

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0010053